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RAP1GAP 抗体 (AA 11-661) (HRP)

The HRP-conjugated 兔 多克隆 anti-RAP1GAP antibody (ABIN8030476) specifically detects RAP1GAP in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8030476
发货至: 中国
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Quick Overview for RAP1GAP 抗体 (AA 11-661) (HRP) (ABIN8030476)

抗原

See all RAP1GAP 抗体
RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

适用

  • 58
  • 37
  • 27
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 11

克隆类型

  • 32
  • 26
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RAP1GAP antibody is conjugated to HRP

应用范围

  • 34
  • 23
  • 19
  • 19
  • 13
  • 13
  • 12
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-661

    原理

    Anti-RAP1GAP Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RAP1GAP recombinant protein (Position: D11-L661).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

    别名

    RAP1GAP

    背景

    Background: Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene. This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

    Gene Full Name: RAP1 GTPase activating protein

    基因ID

    5909

    UniProt

    P47736
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