RAD51AP1 抗体 (AA 1-303) (Cy3)
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北京 101111
Quick Overview for RAD51AP1 抗体 (AA 1-303) (Cy3) (ABIN8030118)
抗原
See all RAD51AP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-303
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原理
- Anti-RAD51AP1 Antibody Cy3 Conjugated
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAD51AP1 recombinant protein (Position: M1-K303).
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亚型
- IgG
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anti-RAD51-Interacting Protein (RAD51AP1) (AA 1-335) antibody
RAD51AP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (C-Term) antibodyVerified RAD51AP1 适用: 人 ELISA, FACS, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 1-335) antibodyRAD51AP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 215-264) antibodyRAD51AP1 适用: 人, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 143-192) antibodyRAD51AP1 适用: 人, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))
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别名
- RAD51AP1
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背景
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Background: The RAD51AP1 gene encodes a protein known as RAD51-associated protein 1, which plays a crucial role in homologous recombination, a DNA repair pathway essential for maintaining genomic integrity. RAD51AP1 interacts with RAD51, a key protein involved in homologous recombination, and promotes the assembly of RAD51 nucleoprotein filaments on single-stranded DNA, facilitating the search for homologous sequences and strand exchange. This process is vital for repairing DNA double-strand breaks and stalled replication forks, as well as for meiotic recombination and telomere maintenance. Dysregulation of RAD51AP1 expression or function has been implicated in cancer development and progression, as defects in homologous recombination can lead to genomic instability and oncogenesis. Understanding the molecular mechanisms underlying RAD51AP1-mediated homologous recombination is crucial for deciphering its role in DNA repair and genome maintenance, as well as for developing targeted therapies for cancer and other diseases associated with DNA damage.
Gene Full Name: RAD51 associated protein 1
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基因ID
- 10635
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UniProt
- Q96B01
抗原
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