RAB7A 抗体 (AA 156-197) (Biotin)
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北京 101111
Quick Overview for RAB7A 抗体 (AA 156-197) (Biotin) (ABIN8029974)
抗原
See all RAB7A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-197
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原理
- Anti-RAB7A Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAB7A recombinant protein (Position: A156-R197).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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别名
- RAB7A
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背景
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Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end ed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
Gene Full Name: RAB7A, member RAS oncogene family
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基因ID
- 7879
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UniProt
- P51149
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途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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