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PNP 抗体 (AA 44-273)

This 兔 多克隆 antibody specifically detects PNP in WB, ELISA 和 FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8028977
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PNP 抗体 (AA 44-273) (ABIN8028977)

抗原

See all PNP 抗体
PNP (Purine Nucleoside Phosphorylase (PNP))

适用

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人, 大鼠, 小鼠

宿主

  • 52
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  • 1
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克隆类型

  • 54
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多克隆

标记

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This PNP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

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    AA 44-273

    原理

    Anti-PNP Antibody

    预测反应

    Human PNP shares 86.5%,87% amino acid (aa) sequence identity with mouse,rat PNP,respectively.

    产品特性

    Anti-PNP Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PNP recombinant protein (Position: Q44-Q273). Human PNP shares 86.5% and 87% amino acid (aa) sequence identity with mouse and rat PNP, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PNP (Purine Nucleoside Phosphorylase (PNP))

    别名

    PNP

    背景

    Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

    Gene Full Name: purine nucleoside phosphorylase

    分子量

    32 kDa

    基因ID

    4860

    UniProt

    P00491

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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