PNP 抗体 (AA 44-273) (PE)
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Quick Overview for PNP 抗体 (AA 44-273) (PE) (ABIN8028975)
抗原
See all PNP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-273
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原理
- Anti-PNP Antibody PE Conjugated
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预测反应
- Human PNP shares 86.5%,87% amino acid (aa) sequence identity with mouse,rat PNP,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNP recombinant protein (Position: Q44-Q273). Human PNP shares 86.5% and 87% amino acid (aa) sequence identity with mouse and rat PNP, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PNP (Purine Nucleoside Phosphorylase (PNP))
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别名
- PNP
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背景
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Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
Gene Full Name: purine nucleoside phosphorylase
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基因ID
- 4860
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UniProt
- P00491
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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