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PNP 抗体 (AA 44-273) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-PNP antibody (ABIN8028967) specifically detects PNP in WB, ELISA 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8028967
发货至: 中国
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Quick Overview for PNP 抗体 (AA 44-273) (Biotin) (ABIN8028967)

抗原

See all PNP 抗体
PNP (Purine Nucleoside Phosphorylase (PNP))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PNP antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 44-273

    原理

    Anti-PNP Antibody Biotin Conjugated

    预测反应

    Human PNP shares 86.5%,87% amino acid (aa) sequence identity with mouse,rat PNP,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PNP recombinant protein (Position: Q44-Q273). Human PNP shares 86.5% and 87% amino acid (aa) sequence identity with mouse and rat PNP, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PNP (Purine Nucleoside Phosphorylase (PNP))

    别名

    PNP

    背景

    Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

    Gene Full Name: purine nucleoside phosphorylase

    基因ID

    4860

    UniProt

    P00491

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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