PNP 抗体 (Middle Region) (FITC)
Our Local Distributor
北京 101111
Quick Overview for PNP 抗体 (Middle Region) (FITC) (ABIN8028961)
抗原
See all PNP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Middle Region
-
原理
- Anti-PNP Antibody (monoclonal, 2H10) FITC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
预测反应
- different from the related mouse sequence by six amino acids,and from the related rat sequence by five amino acids.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
-
亚型
- IgG2b
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- PNP (Purine Nucleoside Phosphorylase (PNP))
-
别名
- PNP
-
背景
-
Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.
Gene Full Name: purine nucleoside phosphorylase
-
基因ID
- 4860
-
UniProt
- P00491
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
-