PCDHa13 抗体 (AA 165-349) (Biotin)
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Quick Overview for PCDHa13 抗体 (AA 165-349) (Biotin) (ABIN8028681)
抗原
See all PCDHa13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 165-349
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原理
- Anti-PCDHA13 Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PCDHA13 shares 58.9% amino acid (aa) sequence identity with mouse PCDHA13.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCDHA13 recombinant protein (Position: N165-E349). Human PCDHA13 shares 58.9% amino acid (aa) sequence identity with mouse PCDHA13.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PCDHa13 (Protocadherin alpha 13 (PCDHa13))
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别名
- PCDHA13
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背景
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Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Gene Full Name: protocadherin alpha 13
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基因ID
- 56136
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UniProt
- Q9Y5I0
抗原
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