PCMT1 抗体 (AA 1-227) (APC)
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Quick Overview for PCMT1 抗体 (AA 1-227) (APC) (ABIN8028578)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-227
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原理
- Anti-PCMT1 Antibody APC Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PCMT1 shares 96%,95.6% amino acid (aa) sequence identity with mouse,rat PCMT1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCMT1 recombinant protein (Position: M1-K227). Human PCMT1 shares 96% and 95.6% amino acid (aa) sequence identity with mouse and rat PCMT1, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- PCMT1
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背景
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Background: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase
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基因ID
- 5110
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UniProt
- P22061
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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