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PKC eta 抗体 (AA 30-389) (Fluoro647)

This 兔 多克隆 antibody specifically detects PKC eta in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8027507
发货至: 中国
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Quick Overview for PKC eta 抗体 (AA 30-389) (Fluoro647) (ABIN8027507)

抗原

See all PKC eta (PRKCH) 抗体
PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC eta antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 30-389

    原理

    Anti-PKC eta/PRKCH Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human PKC eta shares 96.7%,96.1% amino acid (aa) sequence identity with mouse,rat PKC eta,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PKC eta recombinant protein (Position: R30-D389). Human PKC eta shares 96.7% and 96.1% amino acid (aa) sequence identity with mouse and rat PKC eta, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

    别名

    PRKCH

    背景

    Background: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

    Gene Full Name: protein kinase C eta

    Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

    基因ID

    5583

    UniProt

    P24723

    途径

    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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