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PDIA3 抗体 (C-Term) (HRP)

The HRP-conjugated 小鼠 单克隆 anti-PDIA3 antibody (Clone 7E5) (ABIN8027218) specifically detects PDIA3 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8027218
发货至: 中国
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北京 101111
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Quick Overview for PDIA3 抗体 (C-Term) (HRP) (ABIN8027218)

抗原

See all PDIA3 抗体
PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

适用

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宿主

  • 108
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  • 3
小鼠

克隆类型

  • 92
  • 60
单克隆

标记

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This PDIA3 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

7E5
  • 抗原表位

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    C-Term

    原理

    Anti-ERp57 Antibody (monoclonal, 7E5) HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse,rat sequences by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ERp57, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG1
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

    别名

    PDIA3

    背景

    Background: PDIA3 (Protein disulfide isomerase family A, member 3), also called GRP58, Erp57 or ER60, is an isomerase enzyme. It is mapped on 15q15.3. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex, which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

    Gene Full Name: protein disulfide isomerase family A member 3

    基因ID

    2923

    UniProt

    P30101

    途径

    Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
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