Prosaposin 抗体 (AA 182-479)
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Quick Overview for Prosaposin 抗体 (AA 182-479) (ABIN8026224)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 182-479
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原理
- Anti-PSAP Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PSAP Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PSAP recombinant protein (Position: Q182-I479).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Prosaposin (PSAP)
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别名
- PSAP
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背景
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Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Gene Full Name: prosaposin
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分子量
- 70 kDa
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基因ID
- 5660
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UniProt
- P07602
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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