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P4HB 抗体 (AA 146-363) (APC)

This 兔 多克隆 antibody specifically detects P4HB in FACS. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN8026001
发货至: 中国
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Quick Overview for P4HB 抗体 (AA 146-363) (APC) (ABIN8026001)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

  • 143
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人, 小鼠, 大鼠, 猴

宿主

  • 157
  • 27
  • 2

克隆类型

  • 125
  • 61
多克隆

标记

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This P4HB antibody is conjugated to APC

应用范围

  • 144
  • 89
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  • 38
  • 17
  • 14
  • 14
  • 12
  • 5
  • 4
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  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 19
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    • 15
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    • 4
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    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 146-363

    原理

    Anti-P4HB Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human P4HB recombinant protein (Position: A146-D363).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    P4HB

    背景

    Background: Protein disulfide-isomerase, also known as the beta-subunit of prolyl 4-hydroxylase (P4HB), is an enzyme that in humans encoded by the P4HB gene. This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

    Gene Full Name: prolyl 4-hydroxylase subunit beta

    基因ID

    5034

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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