PRR5 抗体 (AA 45-366) (Fluoro594)
Our Local Distributor
北京 101111
Quick Overview for PRR5 抗体 (AA 45-366) (Fluoro594) (ABIN8025888)
抗原
See all PRR5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 45-366
-
原理
- Anti-PRR5 Antibody Fluoro594 Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PRR5 recombinant protein (Position: S45-D366).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- PRR5 (Proline Rich 5 (Renal) (PRR5))
-
别名
- PRR5
-
背景
-
Background: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Gene Full Name: proline rich 5
-
基因ID
- 55615
-
UniProt
- P85299
-
途径
- PI3K-Akt Signaling
抗原
-