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Prolactin Receptor 抗体 (C-Term) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-Prolactin Receptor antibody (ABIN8025781) specifically detects Prolactin Receptor in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8025781
发货至: 中国
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Quick Overview for Prolactin Receptor 抗体 (C-Term) (Fluoro647) (ABIN8025781)

抗原

See all Prolactin Receptor (PRLR) 抗体
Prolactin Receptor (PRLR)

适用

  • 154
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人, 大鼠, 小鼠

宿主

  • 95
  • 50
  • 14
  • 2
  • 1

克隆类型

  • 84
  • 74
  • 3
多克隆

标记

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This Prolactin Receptor antibody is conjugated to Fluoro647

应用范围

  • 68
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Flow Cytometry (FACS)
  • 抗原表位

    • 23
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    • 2
    • 2
    • 1
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    C-Term

    原理

    Anti-Prolactin Receptor/PRLR Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence,and different from the related human sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse PRLR, identical to the related rat sequence, and different from the related human sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Prolactin Receptor (PRLR)

    别名

    PRLR

    背景

    Background: PRLR (Prolactin Receptor), is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al. (1989, 1990) demonstrated that the prolactin receptor gene resides in the same chromosomal region as the growth hormone receptor gene, which has been mapped to 5p13-p12. Cunningham et al. (1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to the growth hormone receptor or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues (histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRL receptors but not GH receptors) are likely zinc-ion ligands.

    Gene Full Name: prolactin receptor

    Sequence Similarities: Belongs to the type I cytokine receptor family. Type 1 subfamily.

    基因ID

    19116

    UniProt

    Q08501

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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