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Prolactin Receptor 抗体 (C-Term)

The 兔 多克隆 anti-Prolactin Receptor antibody is suitable to detect Prolactin Receptor in samples from 人. It has been validated for WB.
产品编号 ABIN8025771
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Prolactin Receptor 抗体 (C-Term) (ABIN8025771)

抗原

See all Prolactin Receptor (PRLR) 抗体
Prolactin Receptor (PRLR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prolactin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

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    C-Term

    原理

    Anti-Prolactin Receptor/PRLR Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by eleven amino acids,and from the related rat sequence by fourteen amino acids.

    产品特性

    Anti-Prolactin Receptor/PRLR Antibody. Tested in WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PRLR, different from the related mouse sequence by eleven amino acids, and from the related rat sequence by fourteen amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Prolactin Receptor (PRLR)

    别名

    PRLR

    背景

    Background: PRLR (Prolactin Receptor) is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al. (1989, 1990) demonstrated that the prolactin receptor gene resides in the same chromosomal region as the growth hormone receptor gene, which has been mapped to 5p13-p12. Cunningham et al. (1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to the growth hormone receptor or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues (histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRL receptors but not GH receptors) are likely zinc-ion ligands.

    Gene Full Name: prolactin receptor

    分子量

    90 kDa

    基因ID

    5618

    UniProt

    P16471

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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