Prohibitin 2 抗体 (AA 1-299)
Our Local Distributor
北京 101111
Quick Overview for Prohibitin 2 抗体 (AA 1-299) (ABIN8025683)
抗原
See all Prohibitin 2 (PHB2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 1-299
-
原理
- Anti-REA/PHB2 Antibody (monoclonal, 2B5)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-REA/PHB2 Antibody.(monoclonal, 2B5). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human REA/PHB2 recombinant protein (Position: M1-K299).
-
亚型
- IgG2b
-
-
anti-Prohibitin 2 (PHB2) antibody
PHB2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Prohibitin 2 (PHB2) (AA 225-255) antibodyPHB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15576 unconjugated
anti-Prohibitin 2 (PHB2) (AA 197-226), (C-Term) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10631 unconjugated
anti-Prohibitin 2 (PHB2) (Tyr128) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 106-134) antibodyPHB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15314 unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1555 unconjugated Recombinant Antibody
-
-
应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- Prohibitin 2 (PHB2)
-
别名
- PHB2
-
背景
-
Background: PHB2 (Prohibitin 2), also called Repressor of Estrogen Receptor Activity (REA), is a protein that in humans is encoded by the PHB2 gene. The International Radiation Hybrid Mapping Consortium mapped the PHB2 gene to chromosome 12. Montano et al. (1999) showed that REA enhanced the potency of a dominant-negative ER-alpha mutant and antiestrogens as suppressors of ER-alpha activity in Chinese hamster ovary cells. When coexpressed with wildtype ER-alpha or ER-beta (ESR2), REA suppressed activation of a < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>reporter gene in a dose-dependent manner. REA had no effect on reporter activity in the absence of liganded ER, and it had no effect on the transcriptional activities of other hormone receptors. Mutation analysis showed that an N-terminal domain and a central domain of REA were required for its repressor activity.
Gene Full Name: prohibitin 2
-
分子量
- 32 kDa
-
基因ID
- 11331
-
UniProt
- Q99623
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
-
