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PFN2 抗体 (AA 96-138) (PE)

The PE-conjugated 兔 多克隆 anti-PFN2 antibody (ABIN8025415) specifically detects PFN2 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8025415
发货至: 中国
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Quick Overview for PFN2 抗体 (AA 96-138) (PE) (ABIN8025415)

抗原

See all PFN2 抗体
PFN2 (Profilin 2 (PFN2))

适用

  • 71
  • 37
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 71
  • 3

克隆类型

  • 71
  • 3
多克隆

标记

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  • 8
  • 4
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
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This PFN2 antibody is conjugated to PE

应用范围

  • 52
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  • 13
  • 13
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 16
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    • 12
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
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    AA 96-138

    原理

    Anti-Profilin 2/PFN2 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Profilin 2/PFN2 recombinant protein (Position: E96-S138).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PFN2 (Profilin 2 (PFN2))

    别名

    PFN2

    背景

    Background: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

    Gene Full Name: profilin 2

    基因ID

    5217

    UniProt

    P35080

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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