PRNP 抗体 (Middle Region)
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北京 101111
Quick Overview for PRNP 抗体 (Middle Region) (ABIN8025262)
抗原
See all PRNP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Middle Region
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原理
- Anti-Prion protein PrP/PRNP Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat sequence.
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产品特性
- Anti-Prion protein PrP/PRNP Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse PRNP, identical to the related rat sequence.
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亚型
- IgG
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anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G9 unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-64) antibodyPRNP 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, IHC, ELISA, IP, IHC (p) 宿主: 兔 Polyclonal T16-R unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal EM-20 unconjugated
anti-Prion Protein (PRNP) (Prion) antibodyPRNP 适用: 人 WB 宿主: 小鼠 Monoclonal EM-20 unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1945 unconjugated Recombinant Antibody
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse Western blot, 0.1-0.5 μg/mL, Rat, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PRNP (Prion Protein (PRNP))
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别名
- PRNP
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背景
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Background: PRNP (prion protein), also known as CD230 and PRP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6 % similarity in amino acid sequences.
Gene Full Name: prion protein
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分子量
- 28 kDa
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基因ID
- 19122
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UniProt
- P04925
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途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
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