电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PRNP 抗体 (Middle Region) (HRP)

The 兔 多克隆 anti-PRNP antibody is suitable to detect PRNP in samples from 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8025258
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRNP 抗体 (Middle Region) (HRP) (ABIN8025258)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

  • 146
  • 92
  • 76
  • 20
  • 13
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 140
  • 30
  • 16
  • 2
  • 2
  • 1

克隆类型

  • 110
  • 81
多克隆

标记

  • 65
  • 14
  • 12
  • 9
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PRNP antibody is conjugated to HRP

应用范围

  • 85
  • 46
  • 43
  • 40
  • 27
  • 26
  • 15
  • 15
  • 15
  • 9
  • 7
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 24
    • 15
    • 15
    • 12
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-Prion protein PrP/PRNP Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of mouse PRNP, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRNP

    背景

    Background: PRNP (prion protein), also known as CD230 and PRP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6 % similarity in amino acid sequences.

    Gene Full Name: prion protein

    基因ID

    19122

    UniProt

    P04925

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
You are here: