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PRNP 抗体 (Middle Region) (FITC)

This 兔 多克隆 antibody specifically detects PRNP in FACS. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN8025257
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRNP 抗体 (Middle Region) (FITC) (ABIN8025257)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

  • 146
  • 92
  • 76
  • 20
  • 13
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 140
  • 30
  • 16
  • 2
  • 2
  • 1

克隆类型

  • 110
  • 81
多克隆

标记

  • 65
  • 13
  • 12
  • 9
  • 9
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PRNP antibody is conjugated to FITC

应用范围

  • 86
  • 47
  • 42
  • 41
  • 27
  • 26
  • 15
  • 15
  • 15
  • 9
  • 7
  • 3
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 24
    • 15
    • 15
    • 12
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-Prion protein PrP/PRNP Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of mouse PRNP, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRNP

    背景

    Background: PRNP (prion protein), also known as CD230 and PRP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6 % similarity in amino acid sequences.

    Gene Full Name: prion protein

    基因ID

    19122

    UniProt

    P04925

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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