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PRAME 抗体 (AA 21-509)

The 兔 多克隆 anti-PRAME antibody (ABIN8025094) specifically detects PRAME in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8025094
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRAME 抗体 (AA 21-509) (ABIN8025094)

抗原

See all PRAME 抗体
PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRAME antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

质量等级

Carrier-free
  • 抗原表位

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    AA 21-509

    原理

    Anti-PRAME Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRAME.Antibody-2. Tested in ELISA, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PRAME recombinant protein (Position: T21-N509).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

    别名

    PRAME

    背景

    Background: Melanoma antigen preferentially expressed in tumors is a protein that in humans is encoded by the PRAME gene. It is mapped to 22q11.22. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

    Gene Full Name: PRAME nuclear receptor transcriptional regulator

    分子量

    58 kDa

    基因ID

    23532

    UniProt

    P78395

    途径

    Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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