PRDM8 抗体 (AA 14-405) (APC)
Our Local Distributor
北京 101111
Quick Overview for PRDM8 抗体 (AA 14-405) (APC) (ABIN8025001)
抗原
See all PRDM8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 14-405
-
原理
- Anti-PRDM8 Antibody APC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PRDM8 recombinant protein (Position: D14-D405).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- PRDM8 (PR Domain Containing 8 (PRDM8))
-
别名
- PRDM8
-
背景
-
Background: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.
Gene Full Name: PR/SET domain 8
-
基因ID
- 56978
-
UniProt
- Q9NQV8
抗原
-