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PF4 抗体 (C-Term) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-PF4 antibody (ABIN8023114) specifically detects PF4 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8023114
发货至: 中国
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Quick Overview for PF4 抗体 (C-Term) (Fluoro550) (ABIN8023114)

抗原

See all PF4 抗体
PF4 (Platelet Factor 4 (PF4))

适用

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宿主

  • 133
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克隆类型

  • 124
  • 45
多克隆

标记

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This PF4 antibody is conjugated to Fluoro550

应用范围

  • 105
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Flow Cytometry (FACS)
  • 抗原表位

    • 32
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    C-Term

    原理

    Anti-Platelet factor 4 PF4 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PF4.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PF4 (Platelet Factor 4 (PF4))

    别名

    PF4

    背景

    Background: CXCL4, Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. CXCL4 belongs to the CXC chemokine family. The CXCL4 gene contains 3 exons spanning approximately 1 kb. The gene is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

    Gene Full Name: platelet factor 4

    Sequence Similarities: Belongs to the intercrine alpha (chemokine CxC) family.

    基因ID

    5196

    UniProt

    P02776
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