PNN 抗体 (AA 2-241) (Fluoro647)
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北京 101111
Quick Overview for PNN 抗体 (AA 2-241) (Fluoro647) (ABIN8022599)
抗原
See all PNN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-241
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原理
- Anti-PNN/DRSP Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNN/DRSP recombinant protein (Position: A2-L241).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PNN (Pinin, Desmosome Associated Protein (PNN))
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别名
- PNN
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背景
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Background: Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75 (SRSF4, 601940), SRM300 (SRRM2, 606032), and SRRP130 (PNISR, 616653). Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.
Gene Full Name: pinin, desmosome associated protein
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基因ID
- 5411
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UniProt
- Q9H307
抗原
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