PINX1 抗体 (N-Term) (APC)
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北京 101111
Quick Overview for PINX1 抗体 (N-Term) (APC) (ABIN8022586)
抗原
See all PINX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-PINX1 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by three amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PINX1, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-100) antibody
PINX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 225-275) antibodyPINX1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Internal Region) antibodyPINX1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 85-133) antibodyPINX1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 225-237) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (N-Term) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 151-299) antibodyPINX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-221) antibodyPINX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 35-84) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig, 豚鼠, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 107-156) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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别名
- PINX1
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背景
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Background: PINX1, also known as PIN2 interacting protein 1, is a telomerase inhibitor and a possible tumor suppressor. It is mapped to 8p23. Over-expression of PINX1 results in decreased telomerase activity, telomere shortening, and induction of crisis. Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres. PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity. The PINX1 budding yeast orthologue Gnop1 inhibits telomerase by isolating the uncomplexed TERT protein so that it cannot associate with the telomerase template RNA, which prevents telomerase from being assembled. However, in humans, PINX1 impedes already assembled telomerase.
Gene Full Name: PIN2 (TERF1) interacting telomerase inhibitor 1
Sequence Similarities: Belongs to the PINX1 family.
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基因ID
- 54984
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UniProt
- Q96BK5
抗原
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