PYGL 抗体 (AA 313-804) (Fluoro647)
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北京 101111
Quick Overview for PYGL 抗体 (AA 313-804) (Fluoro647) (ABIN8022432)
抗原
See all PYGL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 313-804
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原理
- Anti-PYGL Antibody Fluoro647 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PYGL recombinant protein (Position: K313-K804).
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亚型
- IgG
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anti-phosphorylase, Glycogen, Liver (PYGL) (AA 370-538) antibody
PYGL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 1-280) antibodyPYGL 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 2-846) antibodyPYGL 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) antibodyPYGL 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 1-847) antibodyPYGL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 809-843) antibodyPYGL 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB53470 unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (Internal Region) antibodyPYGL 适用: 人, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (C-Term) antibodyPYGL 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) (AA 341-509) antibodyPYGL 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphorylase, Glycogen, Liver (PYGL) antibodyPYGL 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PYGL (phosphorylase, Glycogen, Liver (PYGL))
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别名
- PYGL
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背景
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Background: Glycogen phosphorylase, liver form (PYGL), also known as human liver glycogen phosphorylase (HLGP), is an enzyme that in humans is encoded by the PYGL gene on chromosome 14. This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: glycogen phosphorylase L
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基因ID
- 5836
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UniProt
- P06737
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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