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PMVK 抗体 (Middle Region) (APC)

This 兔 多克隆 antibody specifically detects PMVK in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8022308
发货至: 中国
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Quick Overview for PMVK 抗体 (Middle Region) (APC) (ABIN8022308)

抗原

See all PMVK 抗体
PMVK (Phosphomevalonate Kinase (PMVK))

适用

人, 小鼠, 大鼠

宿主

  • 54
  • 10

克隆类型

  • 55
  • 8
多克隆

标记

  • 27
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PMVK antibody is conjugated to APC

应用范围

  • 45
  • 21
  • 16
  • 13
  • 13
  • 10
  • 7
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 13
    • 7
    • 2
    • 1
    • 1
    Middle Region

    原理

    Anti-Phosphomevalonate kinase PMVK Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse sequence,and different from the related rat sequence by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PMVK, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PMVK (Phosphomevalonate Kinase (PMVK))

    别名

    PMVK

    背景

    Background: PMVK (phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence (PTS-1), Ser-Arg-Leu, at the C terminus of the protein.

    Gene Full Name: phosphomevalonate kinase

    基因ID

    10654

    UniProt

    Q15126
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