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PLD1 抗体 (AA 1-330) (HRP)

The 兔 多克隆 anti-PLD1 antibody is suitable to detect PLD1 in samples from 人 和 小鼠. It has been validated for ELISA, WB 和 IHC.
产品编号 ABIN8022219
发货至: 中国
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Quick Overview for PLD1 抗体 (AA 1-330) (HRP) (ABIN8022219)

抗原

See all PLD1 抗体
PLD1 (Phospholipase D1 (PLD1))

适用

  • 42
  • 19
  • 8
人, 小鼠

宿主

  • 39
  • 3

克隆类型

  • 40
  • 2
多克隆

标记

  • 22
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PLD1 antibody is conjugated to HRP

应用范围

  • 16
  • 15
  • 8
  • 6
  • 5
  • 3
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 11
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-330

    原理

    Anti-Phospholipase D1/PLD1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human PLD1 shares 91.8%,90.9% amino acid (aa) sequence identity with mouse,rat PLD1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PLD1 (Phospholipase D1 (PLD1))

    别名

    PLD1

    背景

    Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

    Gene Full Name: phospholipase D1

    Sequence Similarities: Belongs to the phospholipase D family.

    基因ID

    5337

    UniProt

    Q13393
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