PIK3R5 抗体 (AA 170-864) (Fluoro488)
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Quick Overview for PIK3R5 抗体 (AA 170-864) (Fluoro488) (ABIN8021914)
抗原
See all PIK3R5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-864
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原理
- Anti-PIK3R5 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PIK3R5 recombinant protein (Position: E170-L864). Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
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别名
- PIK3R5
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背景
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Background: Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
Gene Full Name: phosphoinositide-3-kinase regulatory subunit 5
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基因ID
- 23533
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UniProt
- Q8WYR1
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途径
- PI3K-Akt Signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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