PIK3C2A 抗体 (AA 22-1523) (FITC)
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Quick Overview for PIK3C2A 抗体 (AA 22-1523) (FITC) (ABIN8021895)
抗原
See all PIK3C2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-1523
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原理
- Anti-PIK3C2A Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PIK3C2A recombinant protein (Position: R22-E1523). Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
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别名
- PIK3C2A
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背景
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Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Gene Full Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
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基因ID
- 5286
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UniProt
- O00443
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途径
- EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling
抗原
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