PIK3AP1 抗体 (AA 78-583) (Biotin)
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北京 101111
Quick Overview for PIK3AP1 抗体 (AA 78-583) (Biotin) (ABIN8021846)
抗原
See all PIK3AP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 78-583
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原理
- Anti-PIK3AP1 Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PIK3AP1 recombinant protein (Position: H78-R583). Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.
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亚型
- IgG
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anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibody
PIK3AP1 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 7G9 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibodyPIK3AP1 适用: 人, 大鼠, 猴 WB, FACS 宿主: 小鼠 Monoclonal 6H6 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 489-730) antibodyPIK3AP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 601-700) antibodyPIK3AP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 639-668), (C-Term) antibodyPIK3AP1 适用: 人 WB 宿主: 兔 Polyclonal RB32640 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 293-404) antibodyPIK3AP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 397-650) antibodyPIK3AP1 适用: 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))
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别名
- PIK3AP1
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背景
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Background: Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.
Gene Full Name: phosphoinositide-3-kinase adaptor protein 1
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基因ID
- 118788
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UniProt
- Q6ZUJ8
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途径
- Activation of Innate immune Response, BCR Signaling, Warburg Effect
抗原
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