PDE8B 抗体 (C-Term) (Biotin)
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北京 101111
Quick Overview for PDE8B 抗体 (C-Term) (Biotin) (ABIN8021558)
抗原
See all PDE8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-PDE8B Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PDE8B. Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
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Background: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: phosphodiesterase 8B
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基因ID
- 8622
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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