PHF8 抗体 (AA 108-946) (FITC)
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北京 101111
Quick Overview for PHF8 抗体 (AA 108-946) (FITC) (ABIN8021048)
抗原
See all PHF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-946
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原理
- Anti-PHF8 Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PHF8 (PHD Finger Protein 8 (PHF8))
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别名
- PHF8
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背景
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Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: PHD finger protein 8
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基因ID
- 23133
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UniProt
- Q9UPP1
抗原
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