PEX19 抗体 (AA 51-269) (Cy3)
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Quick Overview for PEX19 抗体 (AA 51-269) (Cy3) (ABIN8020762)
抗原
See all PEX19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-269
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原理
- Anti-PEX19 Antibody Cy3 Conjugated
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预测反应
- Human PEX19 shares 91.8%,94.5% amino acid (aa) sequence identity with mouse,rat PEX19,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PEX19 recombinant protein (Position: Q51-A269). Human PEX19 shares 91.8% and 94.5% amino acid (aa) sequence identity with mouse and rat PEX19, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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别名
- PEX19
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背景
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Background: Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene. This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Gene Full Name: peroxisomal biogenesis factor 19
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基因ID
- 5824
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UniProt
- P40855
抗原
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