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Peroxiredoxin 3 抗体 (C-Term) (HRP)

The 兔 多克隆 anti-Peroxiredoxin 3 antibody is suitable to detect Peroxiredoxin 3 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8020644
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Peroxiredoxin 3 抗体 (C-Term) (HRP) (ABIN8020644)

抗原

See all Peroxiredoxin 3 (PRDX3) 抗体
Peroxiredoxin 3 (PRDX3)

适用

  • 147
  • 75
  • 58
  • 2
人, 大鼠, 小鼠

宿主

  • 145
  • 11
  • 1

克隆类型

  • 118
  • 38
多克隆

标记

  • 59
  • 16
  • 9
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Peroxiredoxin 3 antibody is conjugated to HRP

应用范围

  • 102
  • 61
  • 52
  • 32
  • 29
  • 29
  • 25
  • 14
  • 13
  • 13
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 26
    • 15
    • 15
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Peroxiredoxin 3/PRDX3 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence,and different from the related human sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Peroxiredoxin 3, identical to the related rat sequence, and different from the related human sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Peroxiredoxin 3 (PRDX3)

    别名

    PRDX3

    背景

    Background: PRDX3 (peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86% amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that PRDX3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.

    Gene Full Name: peroxiredoxin 3

    Sequence Similarities: Belongs to the AhpC/TSA family.

    基因ID

    11757

    UniProt

    P20108

    途径

    Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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