Peroxiredoxin 3 抗体 (AA 110-256) (APC)
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Quick Overview for Peroxiredoxin 3 抗体 (AA 110-256) (APC) (ABIN8020623)
抗原
See all Peroxiredoxin 3 (PRDX3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-256
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原理
- Anti-Peroxiredoxin 3/PRDX3 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human Peroxiredoxin 3 shares 93% amino acid (aa) sequence identity with both mouse,rat Peroxiredoxin 3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Peroxiredoxin 3 recombinant protein (Position: T110-Q256). Human Peroxiredoxin 3 shares 93% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 3.
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亚型
- IgG
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anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibody
PRDX3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 5-233) antibodyPRDX3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyKD Validated PRDX3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB935 unconjugated Recombinant Antibody
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 63-256) antibodyPRDX3 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 110-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1E3-B2 unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 66-94), (N-Term) antibodyPRDX3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20889 unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 239-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Peroxiredoxin 3 (PRDX3)
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别名
- PRDX3
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背景
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Background: PRDX3 (peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86 % amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that PRDX3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.
Gene Full Name: peroxiredoxin 3
Sequence Similarities: Belongs to the AhpC/TSA family.
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基因ID
- 10935
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UniProt
- P30048
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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