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PER2 抗体 (AA 13-330) (APC)

The APC-conjugated 兔 多克隆 anti-PER2 antibody (ABIN8020501) specifically detects PER2 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8020501
发货至: 中国
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Quick Overview for PER2 抗体 (AA 13-330) (APC) (ABIN8020501)

抗原

See all PER2 抗体
PER2 (Period Circadian Protein 2 (PER2))

适用

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  • 35
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宿主

  • 79
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克隆类型

  • 68
  • 15
多克隆

标记

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This PER2 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 13-330

    原理

    Anti-PER2 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human PER2 shares 84%,83% amino acid (aa) sequence identity with mouse,rat PER2,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PER2 recombinant protein (Position: N13-K330). Human PER2 shares 84% and 83% amino acid (aa) sequence identity with mouse and rat PER2, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PER2 (Period Circadian Protein 2 (PER2))

    别名

    PER2

    背景

    Background: The PER2 gene encodes the period circadian protein homolog 2 protein in humans. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. PER2 is mapped to 2q37.3. It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, in turn, Npas2 transcriptionally regulates delta-aminolevulinate synthase. PER2 is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling. The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms. What's more, the PER2 gene also functions in tumor suppression by regulating DNA damage-responsive pathways.

    Gene Full Name: period circadian regulator 2

    Sequence Similarities: Contains 1 PAC (PAS-associated C-terminal) domain.

    基因ID

    8864

    UniProt

    O15055
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