PIN1 抗体 (AA 1-163) (HRP)
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北京 101111
Quick Overview for PIN1 抗体 (AA 1-163) (HRP) (ABIN8020279)
抗原
See all PIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-163
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原理
- Anti-Pin1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Pin1 shares 95% amino acid (aa) sequence identity with mouse Pin1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Pin1 recombinant protein (Position: M1-E163). Human Pin1 shares 95% amino acid (aa) sequence identity with mouse Pin1.
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亚型
- IgG
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anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 30-56) antibody
PIN1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22881 unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-163) antibodyPIN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 30-56) antibodyPIN1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-163) antibodyPIN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (pSer16) antibodyPIN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) antibodyPIN1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 小鸡 Polyclonal unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) antibodyKD Validated PIN1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7330 unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) antibodyKD Validated PIN1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7285 unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) antibodyPIN1 适用: 人, 小鼠, 大鼠, Green Monkey IHC (p), IF (cc) 宿主: 小鼠 Monoclonal 5F5 unconjugated
anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 2-163) antibodyPIN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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别名
- PIN1
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背景
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Background: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, also called DOD, is an enzyme that in humans is encoded by the PIN1 gene. It is mapped to 19p13.2. The enzyme binds to a subset of proteins and thus plays a role as a post phospho PIN1rol in regulating protein function. Studies have shown that the deregulation of PIN1 may play a pivotal role in various diseases. Notably, the up-regulation of PIN1 may be implicated in certain cancers, and the down-regulation of Pin1 may be implicated in Alzheimer's disease. Inhibitors of PIN1 may have therapeutic implications for cancer and immune disorders. PIN1 activity regulates the outcome of proline-ed kinase (e.g. MAPK, CDK or GSK3) signalling and consequently regulates cell proliferation (in part through control of cyclin D1 levels and stability) and cell survival. PIN1 also has an essential role in maintaining cell proliferation and regulating cyclin D1 function.
Gene Full Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Sequence Similarities: Contains 1 PpiC domain.
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基因ID
- 5300
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UniProt
- Q13526
抗原
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