PEG3 抗体 (AA 1-1548) (APC)
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Quick Overview for PEG3 抗体 (AA 1-1548) (APC) (ABIN8019787)
抗原
See all PEG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1548
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原理
- Anti-PEG3 Antibody APC Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PEG3 recombinant protein (Position: M1-R1548). Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PEG3 (Paternally Expressed 3 (PEG3))
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别名
- PEG3
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背景
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Background: Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene. In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: paternally expressed 3
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基因ID
- 5178
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UniProt
- Q9GZU2
抗原
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