PNPLA6 抗体 (AA 15-1296) (Fluoro550)
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北京 101111
Quick Overview for PNPLA6 抗体 (AA 15-1296) (Fluoro550) (ABIN8019750)
抗原
See all PNPLA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-1296
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原理
- Anti-PNPLA6 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNPLA6 recombinant protein (Position: H15-E1296).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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别名
- PNPLA6
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背景
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Background: Neuropathy target esterase, also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded by the PNPLA6 gene. This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: patatin like domain 6, lysophospholipase
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基因ID
- 10908
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UniProt
- Q8IY17
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途径
- Ribonucleoside Biosynthetic Process
抗原
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