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PON1 抗体 (Middle Region)

The 兔 多克隆 anti-PON1 antibody is suitable to detect PON1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN8019558
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PON1 抗体 (Middle Region) (ABIN8019558)

抗原

See all PON1 抗体
PON1 (Paraoxonase 1 (PON1))

适用

  • 143
  • 126
  • 110
  • 15
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 159
  • 53
  • 1

克隆类型

  • 139
  • 73
多克隆

标记

  • 71
  • 22
  • 14
  • 13
  • 11
  • 9
  • 9
  • 8
  • 8
  • 8
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PON1 antibody is un-conjugated

应用范围

  • 124
  • 79
  • 78
  • 62
  • 31
  • 16
  • 16
  • 13
  • 13
  • 8
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 72
    • 15
    • 13
    • 13
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-PON1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by three amino acids.

    产品特性

    Anti-PON1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PON1, different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PON1 (Paraoxonase 1 (PON1))

    别名

    PON1

    背景

    Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

    Gene Full Name: paraoxonase 1

    Sequence Similarities: Belongs to the paraoxonase family.

    分子量

    40 kDa

    基因ID

    5444

    UniProt

    P27169
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