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PDX1 抗体 (AA 1-145) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-PDX1 antibody (ABIN8019343) specifically detects PDX1 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8019343
发货至: 中国
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Quick Overview for PDX1 抗体 (AA 1-145) (Fluoro594) (ABIN8019343)

抗原

See all PDX1 抗体
PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

适用

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宿主

  • 157
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克隆类型

  • 140
  • 29
多克隆

标记

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This PDX1 antibody is conjugated to Fluoro594

应用范围

  • 103
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Flow Cytometry (FACS)
  • 抗原表位

    • 16
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    AA 1-145

    原理

    Anti-PDX1 Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human PDX1 shares 87.7%,86.9% amino acid (aa) sequence identity with mouse,rat PDX1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PDX1 recombinant protein (Position: M1-E145). Human PDX1 shares 87.7% and 86.9% amino acid (aa) sequence identity with mouse and rat PDX1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

    别名

    PDX1

    背景

    Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

    Gene Full Name: pancreatic and duodenal homeobox 1

    基因ID

    3651

    UniProt

    P52945

    途径

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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