PAX8 抗体 (AA 137-450) (HRP)
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北京 101111
Quick Overview for PAX8 抗体 (AA 137-450) (HRP) (ABIN8019179)
抗原
See all PAX8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 137-450
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原理
- Anti-PAX8 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PAX8 shares 95.3%,95% amino acid (aa) sequence identity with mouse,rat PAX8,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAX8 recombinant protein (Position: Q137-L450). Human PAX8 shares 95.3% and 95% amino acid (aa) sequence identity with mouse and rat PAX8, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PAX8 (Paired Box 8 (PAX8))
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别名
- PAX8
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背景
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Background: Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Full Name: paired box 8
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基因ID
- 7849
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UniProt
- Q06710
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途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
抗原
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