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PAK6 抗体 (N-Term) (Biotin)

This 兔 多克隆 antibody specifically detects PAK6 in WB, ELISA 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8019008
发货至: 中国
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Quick Overview for PAK6 抗体 (N-Term) (Biotin) (ABIN8019008)

抗原

See all PAK6 抗体
PAK6 (P21-Activated Kinase 6 (PAK6))

适用

  • 71
  • 50
  • 16
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 86

克隆类型

  • 85
多克隆

标记

  • 37
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAK6 antibody is conjugated to Biotin

应用范围

  • 52
  • 27
  • 26
  • 26
  • 14
  • 14
  • 13
  • 10
  • 6
  • 6
  • 6
  • 3
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 14
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-PAK6 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human PAK6, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PAK6 (P21-Activated Kinase 6 (PAK6))

    别名

    PAK6

    背景

    Background: Serine/threonine-protein kinase PAK 6 (p21 Protein-activated Kinase 6) is an enzyme that in humans is encoded by the PAK6 gene. The PAK6 gene is mapped to chromosome 15q15. based on an alignment of the PAK6 sequence with the genomic sequence. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

    Gene Full Name: BUB1B-PAK6 readthrough

    Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

    基因ID

    106821730

    UniProt

    Q9NQU5
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