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OPA1 抗体 (AA 296-562) (HRP)

The HRP-conjugated 兔 多克隆 anti-OPA1 antibody (ABIN8018230) specifically detects OPA1 in WB, IHC 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8018230
发货至: 中国
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Quick Overview for OPA1 抗体 (AA 296-562) (HRP) (ABIN8018230)

抗原

See all OPA1 抗体
OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

适用

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人, 大鼠, 小鼠

宿主

  • 83
  • 4

克隆类型

  • 66
  • 21
多克隆

标记

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This OPA1 antibody is conjugated to HRP

应用范围

  • 53
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 296-562

    原理

    Anti-OPA1 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human OPA1 recombinant protein (Position: D296-Q562).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

    别名

    OPA1

    背景

    Background: Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: OPA1 mitochondrial dynamin like GTPase

    基因ID

    4976

    UniProt

    O60313

    途径

    Tube Formation
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