Mu Opioid Receptor 1 抗体 (AA 33-321) (FITC)
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Quick Overview for Mu Opioid Receptor 1 抗体 (AA 33-321) (FITC) (ABIN8018185)
抗原
See all Mu Opioid Receptor 1 (OPRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-321
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原理
- Anti-OPRM1 Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OPRM1 recombinant protein (Position: N33-H321).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))
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别名
- OPRM1
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背景
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Background: This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.
Gene Full Name: opioid receptor mu 1
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基因ID
- 4988
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UniProt
- P35372
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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