Oncostatin M 抗体 (AA 55-158) (Fluoro488)
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北京 101111
Quick Overview for Oncostatin M 抗体 (AA 55-158) (Fluoro488) (ABIN8018083)
抗原
See all Oncostatin M (OSM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-158
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原理
- Anti-Osm Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Rat Osm shares 46%,71.2% amino acid (aa) sequence identity with human,mouse Osm,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived rat Osm recombinant protein (Position: E55-D158). Rat Osm shares 46% and 71.2% amino acid (aa) sequence identity with human and mouse Osm, respectively.
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亚型
- IgG
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anti-Oncostatin M (OSM) (AA 116-205) antibody
OSM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) antibodyOSM 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-220) antibodyOSM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 25-115) antibodyOSM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) antibodyKD Validated OSM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2640 unconjugated Recombinant Antibody
anti-Oncostatin M (OSM) (AA 26-252) antibodyOSM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 1-252) antibodyOSM 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 1-252) antibodyOSM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (AA 26-220) antibodyOSM 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M (OSM) (Middle Region) antibodyOSM 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Oncostatin M (OSM)
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别名
- Osm
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背景
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Background: OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. OSM has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The ion of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.
Gene Full Name: oncostatin M
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基因ID
- 289747
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UniProt
- Q65Z15
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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