OCRL 抗体 (AA 1-901) (Biotin)
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北京 101111
Quick Overview for OCRL 抗体 (AA 1-901) (Biotin) (ABIN8017916)
抗原
See all OCRL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-901
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原理
- Anti-OCRL Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OCRL recombinant protein (Position: M1-D901).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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别名
- OCRL
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背景
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Background: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
Gene Full Name: OCRL inositol polyphosphate-5-phosphatase
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基因ID
- 4952
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UniProt
- Q01968
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途径
- Inositol Metabolic Process
抗原
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