NUMB 抗体 (AA 59-567) (Cy3)
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北京 101111
Quick Overview for NUMB 抗体 (AA 59-567) (Cy3) (ABIN8017785)
抗原
See all NUMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-567
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原理
- Anti-NUMB Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human NUMB shares 93.7% amino acid (aa) sequence identity with both mouse,rat NUMB.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NUMB recombinant protein (Position: E59-A567). Human NUMB shares 93.7% amino acid (aa) sequence identity with both mouse and rat NUMB.
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亚型
- IgG
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anti-Numb Homolog (NUMB) (C-Term) antibody
Verified NUMB 适用: 人, 小鼠 IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 521-640) antibodyNUMB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) antibodyKD Validated NUMB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1070 unconjugated Recombinant Antibody
anti-Numb Homolog (NUMB) (N-Term) antibodyNUMB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7-A6 unconjugated
anti-Numb Homolog (NUMB) (AA 1-50) antibodyNUMB 适用: 人, 小鼠, 大鼠, 猴, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) antibodyKD Validated NUMB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB940 unconjugated Recombinant Antibody
anti-Numb Homolog (NUMB) (pSer276) antibodyNUMB 适用: 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-214) antibodyNUMB 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NUMB (Numb Homolog (NUMB))
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别名
- NUMB
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背景
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Background: Protein numb homolog is a protein that in humans is encoded by the NUMB gene. It is mapped to 14q24.2 to q24.3. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. The primary function of Numb in cell differentiation is as an inhibitor of Notch signaling which is essential for maintaining self-renewal potential in stem and progenitor cells. Numb also plays a crucial role in asymmetrical cell division during development, allowing for differential cell fate specification in the central and peripheral nervous systems. What's more, the numb gene protein product controls binary cell fate decisions in the peripheral and central nervous systems of both invertebrates and mammals during neurogenesis.
Gene Full Name: NUMB endocytic adaptor protein
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基因ID
- 8650
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UniProt
- P49757
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途径
- Cell-Cell Junction Organization
抗原
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